The Centre for Cardiovascular Telemedicine (TMC) was founded on April 2^nd, 2008 at the Charité and was initially instrumental in the implementation of the clinical study "Telemedical Interventional Monitoring in Heart Failure" (TIM-HF, NCT00543881) within the "Partnership for the Heart" project (funded by the Federal Ministry for Economics and Technology).The development of telemedical product innovations in research projects and their testing in clinical studies is the main field of activity of the TMZ.

The major clinical study was carried out at the TMC from August 2013 to May 2018: Telemedical Interventional Management in Heart Failure II (TIM-HF2, NCT01878630, DRKS00010239), as part of the project "Health Region of the Future North Brandenburg - Fontane" (funded by the Federal Ministry of Education and research).

A new large telemedical research project "Telemed5000", funded by the Federal Ministry for Economic Affairs and Energy, started in August 2019.